cell signaling technology hmgcs2 Search Results


anti hmgcs2 antibody  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc anti hmgcs2 antibody
a Macroscopic appearance of livers from Trmt6 f/+ /Trmt61a f/+ ; Alb-Cre (WT) and Trmt6/Trmt61a DKO ( Trmt6 f/f /Trmt61a f/f ; Alb-Cre) mice under DEN-induced cancer or in Myc OE mouse model of HCC. Black asterisks indicate liver tumors. Scale bar, 1 cm. b Quantitation of liver tumor numbers of Trmt6 KO, Trmt61a KO, and Trmt6/Trmt61a DKO in DEN-treated and in Myc OE mice. Results are shown as means ± SD ( n = 10 biologically independent mice). Exact P values from left to right: 0.0075, 0.041, 0.032, 0.0037, 0.045, 0.014. c Representative liver H&E staining and immunohistochemistry images of m 1 A, Pparδ, and <t>Hmgcs2</t> (brown) from Trmt6 f/ + /Trmt61a f/+ (WT) and Trmt6 −/− /Trmt61a −/− (DKO) in Myc OE and DEN-treated mice. Black circle indicates tumor region. Scale bar, 100 μm. n = 3 independent samples. d Levels of cholesterol biogenesis related proteins in 10-week-old male Trmt6/Trmt61a deleted (DKO) in Myc OE mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. n = 5 biologically independent mice. e Total serum cholesterol levels in 10-week-old normal-fed male Trmt6/Trmt61a deleted Myc OE (DKO) mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. Data are means ± SD. n = 5 mice per group. Exact P values: 0.021. These experiments were repeated three times. * P < 0.05; ** P < 0.01 by two-tailed Student’s t -test.
Anti Hmgcs2 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti hmgcs2 antibody/product/Cell Signaling Technology Inc
Average 94 stars, based on 1 article reviews
anti hmgcs2 antibody - by Bioz Stars, 2026-04
94/100 stars
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anti hmgcs2  (Cell Signaling Technology Inc)
93
Cell Signaling Technology Inc anti hmgcs2
a Macroscopic appearance of livers from Trmt6 f/+ /Trmt61a f/+ ; Alb-Cre (WT) and Trmt6/Trmt61a DKO ( Trmt6 f/f /Trmt61a f/f ; Alb-Cre) mice under DEN-induced cancer or in Myc OE mouse model of HCC. Black asterisks indicate liver tumors. Scale bar, 1 cm. b Quantitation of liver tumor numbers of Trmt6 KO, Trmt61a KO, and Trmt6/Trmt61a DKO in DEN-treated and in Myc OE mice. Results are shown as means ± SD ( n = 10 biologically independent mice). Exact P values from left to right: 0.0075, 0.041, 0.032, 0.0037, 0.045, 0.014. c Representative liver H&E staining and immunohistochemistry images of m 1 A, Pparδ, and <t>Hmgcs2</t> (brown) from Trmt6 f/ + /Trmt61a f/+ (WT) and Trmt6 −/− /Trmt61a −/− (DKO) in Myc OE and DEN-treated mice. Black circle indicates tumor region. Scale bar, 100 μm. n = 3 independent samples. d Levels of cholesterol biogenesis related proteins in 10-week-old male Trmt6/Trmt61a deleted (DKO) in Myc OE mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. n = 5 biologically independent mice. e Total serum cholesterol levels in 10-week-old normal-fed male Trmt6/Trmt61a deleted Myc OE (DKO) mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. Data are means ± SD. n = 5 mice per group. Exact P values: 0.021. These experiments were repeated three times. * P < 0.05; ** P < 0.01 by two-tailed Student’s t -test.
Anti Hmgcs2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti hmgcs2/product/Cell Signaling Technology Inc
Average 93 stars, based on 1 article reviews
anti hmgcs2 - by Bioz Stars, 2026-04
93/100 stars
  Buy from Supplier

Image Search Results


a Macroscopic appearance of livers from Trmt6 f/+ /Trmt61a f/+ ; Alb-Cre (WT) and Trmt6/Trmt61a DKO ( Trmt6 f/f /Trmt61a f/f ; Alb-Cre) mice under DEN-induced cancer or in Myc OE mouse model of HCC. Black asterisks indicate liver tumors. Scale bar, 1 cm. b Quantitation of liver tumor numbers of Trmt6 KO, Trmt61a KO, and Trmt6/Trmt61a DKO in DEN-treated and in Myc OE mice. Results are shown as means ± SD ( n = 10 biologically independent mice). Exact P values from left to right: 0.0075, 0.041, 0.032, 0.0037, 0.045, 0.014. c Representative liver H&E staining and immunohistochemistry images of m 1 A, Pparδ, and Hmgcs2 (brown) from Trmt6 f/ + /Trmt61a f/+ (WT) and Trmt6 −/− /Trmt61a −/− (DKO) in Myc OE and DEN-treated mice. Black circle indicates tumor region. Scale bar, 100 μm. n = 3 independent samples. d Levels of cholesterol biogenesis related proteins in 10-week-old male Trmt6/Trmt61a deleted (DKO) in Myc OE mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. n = 5 biologically independent mice. e Total serum cholesterol levels in 10-week-old normal-fed male Trmt6/Trmt61a deleted Myc OE (DKO) mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. Data are means ± SD. n = 5 mice per group. Exact P values: 0.021. These experiments were repeated three times. * P < 0.05; ** P < 0.01 by two-tailed Student’s t -test.

Journal: Nature Communications

Article Title: N 1 -methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism

doi: 10.1038/s41467-021-26718-6

Figure Lengend Snippet: a Macroscopic appearance of livers from Trmt6 f/+ /Trmt61a f/+ ; Alb-Cre (WT) and Trmt6/Trmt61a DKO ( Trmt6 f/f /Trmt61a f/f ; Alb-Cre) mice under DEN-induced cancer or in Myc OE mouse model of HCC. Black asterisks indicate liver tumors. Scale bar, 1 cm. b Quantitation of liver tumor numbers of Trmt6 KO, Trmt61a KO, and Trmt6/Trmt61a DKO in DEN-treated and in Myc OE mice. Results are shown as means ± SD ( n = 10 biologically independent mice). Exact P values from left to right: 0.0075, 0.041, 0.032, 0.0037, 0.045, 0.014. c Representative liver H&E staining and immunohistochemistry images of m 1 A, Pparδ, and Hmgcs2 (brown) from Trmt6 f/ + /Trmt61a f/+ (WT) and Trmt6 −/− /Trmt61a −/− (DKO) in Myc OE and DEN-treated mice. Black circle indicates tumor region. Scale bar, 100 μm. n = 3 independent samples. d Levels of cholesterol biogenesis related proteins in 10-week-old male Trmt6/Trmt61a deleted (DKO) in Myc OE mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. n = 5 biologically independent mice. e Total serum cholesterol levels in 10-week-old normal-fed male Trmt6/Trmt61a deleted Myc OE (DKO) mice transduced with AAV vectors encoding GFP control (oeGFP) or Pparδ (oePparδ) for 8 days. WT: Trmt6 f/+ /Trmt61a f/+ ; Myc OE mice. Data are means ± SD. n = 5 mice per group. Exact P values: 0.021. These experiments were repeated three times. * P < 0.05; ** P < 0.01 by two-tailed Student’s t -test.

Article Snippet: Anti-HMGCS2 antibody (#20940S) was from Cell Signaling Technology, Inc. (USA).

Techniques: Quantitation Assay, Staining, Immunohistochemistry, Transduction, Control, Two Tailed Test